Disclaimer
CompoundIQ publishes research summaries for informational and educational purposes only. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. Always consult a licensed healthcare provider. Many compounds listed are research chemicals not approved for human use.
C60 (Buckminsterfullerene)
Also known as: C60, Buckminsterfullerene, Carbon 60, Fullerene
C60 is a spherical molecule of 60 carbon atoms (a 'buckyball') that gained longevity interest after a 2012 study (Baati et al.) showed rats given C60 in olive oil lived nearly twice as long as controls. However, this study had significant methodological concerns and has not been replicated. C60 remains highly experimental with very limited safety data in humans.
Risk Level
High RiskDifficulty
Advanced| CAS Number | 99685-96-8 |
| Molecular Formula | C60 |
| Class | Other |
| Category | Longevity Compounds |
Mechanism of Action
C60 is theorized to act as a powerful free radical sponge, with each molecule capable of neutralizing multiple reactive oxygen species without being consumed. It localizes to mitochondrial membranes where oxidative stress is highest. It may also modulate inflammatory pathways and protect against lipid peroxidation. However, the original lifespan study had only 6 rats per group and potential confounds with olive oil controls.
Dosing Research
No established human dosing. Underground protocols use 0.5-1 mg/kg dissolved in olive oil or MCT oil, taken daily or several times per week. C60 must be properly dissolved in oil (not water-soluble). Quality and purity of C60 products vary enormously. No human pharmacokinetic data available.
Side Effects & Risks
Very limited human safety data. Potential concerns include nanoparticle toxicity, pro-oxidant effects under certain conditions (UV exposure), unknown long-term accumulation in tissues, and contamination with solvents used in preparation. The original rat study is considered unreliable by many researchers. High risk due to complete lack of systematic human safety evaluation.
Research Studies
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Disclaimer
CompoundIQ publishes research summaries for informational and educational purposes only. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. Always consult a licensed healthcare provider. Many compounds listed are research chemicals not approved for human use.