Disclaimer
CompoundIQ publishes research summaries for informational and educational purposes only. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. Always consult a licensed healthcare provider. Many compounds listed are research chemicals not approved for human use.
Cardarine
Also known as: GW-501516, Endurobol
Cardarine is not actually a SARM but a PPARδ agonist, often grouped with SARMs commercially. It was developed by GlaxoSmithKline for metabolic and cardiovascular diseases but was abandoned due to cancer findings in rodent studies.
Risk Level
High RiskDifficulty
Intermediate| CAS Number | 317318-70-0 |
| Molecular Formula | C21H18F3NO3S2 |
| Class | Other |
| Category | SARMs |
Mechanism of Action
GW-501516 activates PPARδ receptors, which regulate fatty acid oxidation and energy expenditure. It shifts the body's fuel preference from glucose to fat, dramatically increasing endurance capacity. It also improves lipid profiles by increasing HDL and decreasing LDL.
Dosing Research
Clinical trials used 2.5-10 mg/day. Research community references 10-20 mg/day. Half-life approximately 16-24 hours. Cycles typically 8-12 weeks.
Side Effects & Risks
Cancer development in rodent studies at high doses over extended periods led to drug abandonment. The relevance to humans at lower doses is debated. Limited long-term human safety data.
Research Studies
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Disclaimer
CompoundIQ publishes research summaries for informational and educational purposes only. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. Always consult a licensed healthcare provider. Many compounds listed are research chemicals not approved for human use.