Disclaimer
CompoundIQ publishes research summaries for informational and educational purposes only. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. Always consult a licensed healthcare provider. Many compounds listed are research chemicals not approved for human use.
Meldonium
Also known as: Mildronate
Meldonium is a cardioprotective drug developed in Latvia, widely used in Eastern Europe for heart conditions. It gained international attention after being banned by WADA in 2016, with many athletes testing positive.
Risk Level
Low RiskDifficulty
Intermediate| CAS Number | 76144-81-5 |
| Molecular Formula | C6H14N2O2 |
| Class | Other |
| Category | Other Performance Compounds |
Mechanism of Action
Meldonium inhibits carnitine biosynthesis by blocking gamma-butyrobetaine hydroxylase. This shifts cellular energy metabolism from fatty acid oxidation to glucose oxidation, which is more oxygen-efficient. It also increases nitric oxide production and reduces carnitine-mediated transport of long-chain fatty acids into mitochondria.
Dosing Research
Therapeutic dose: 500-1000 mg/day orally or IV. Typically used in 4-6 week cycles with breaks. Half-life approximately 4-6 hours. Available as capsules or injection in Eastern Europe.
Side Effects & Risks
Generally well-tolerated at therapeutic doses. Possible GI discomfort, allergic reactions. Banned by WADA since 2016. Limited Western safety data. Long-term effects of chronic use not well studied.
Research Studies
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Disclaimer
CompoundIQ publishes research summaries for informational and educational purposes only. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. Always consult a licensed healthcare provider. Many compounds listed are research chemicals not approved for human use.